Predicting potentially fatal conductive disease in sarcoidosis; can cardiac MRI define the risk?
نویسندگان
چکیده
Background Sarcoidosis incidence is approximately 1:135,000 Americans. Cardiac involvement triggers multiple conduction disturbances, the most severe being complete heart block and VT/VF. Non-caseating granulomas have been found in the myocardium in up to 50% of the cases of fatal sarcoidosis, and 67% of patients that died from cardiac causes had myocardial involvement. Late gadolinium enhancement cardiovascular MCMRRI (LGE) has been shown to be more than twice as sensitive for cardiac involvement per current consensus Japanese Ministry of Health criteria and is widely held but, as yet unproven, to be more sensitive than the invasive RV endomyocardial biopsy.
منابع مشابه
The utility of delayed-enhancement and t2-weighted cardiovascular mri for predicting clinical outcomes in patients at high risk for cardiac sarcoidosis
Methods Patients referred for cardiac MRI (CMR) from 01/01/ 2003 to 12/31/2009 in our institution, and who had biopsy proven sarcoidosis without concomitant coronary artery disease, were included. Patients were classified as presenting with a major rhythmic disturbance (MRD) if the referral for cardiac MRI was prompted by high grade atrio-ventricular block, sustained ventricular tachycardia or ...
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عنوان ژورنال:
دوره 15 شماره
صفحات -
تاریخ انتشار 2013